Chlamydial infection in animals

Chlamydophila pecorum

Typing

Jones et al., 1997 have described subtypes of C. pecorum which vary in their ability to cause disease. Rodolakis et al., 1989 reported that C. pecorum isolated from the faeces of sheep were antigenically heterogeneous. Variations in the major outer membrane protein (MOMP) of C. pecorum strains from various conditions have been observed by immunoblotting (Fukushi & Hirai, 1992). However C. pecorum strains from several different immunotypes have been shown to possess identical MOMP sequences (Kaltenboeck et al., 1993). A key challenge is to identify for C. pecorum strains the relationships between immunotype, MOMP or other sequence, biological variation, host tropism and disease (Anderson et al., 1996).

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